CV

Education

University of Oxford, Oxford, UK
- DPhil in Clinical Medicine, Nuffield Department of Medicine & Hertford College, 2020 - 2024 (expected)
Zhejiang University, Hangzhou, ZJ, China
- B.E. in Food Science & Engineering with Honors, Chu Kochen Honors College, 2016 - 2020
University of California, Berkeley, CA, US
- Exchange student, Dept. of Molecular & Cell Biology, 2018 Fall

Oct. 2020 - present: Graduate Research Assistant, WCHG, University of Oxford, Oxford, UK
- Projects:
  1. Applying high-throughput bulk sequencing methods to study the key regulators of atherosclerotic processes in primary human cell models.
  2. Dissecting the role of human macrophage heterogeneity in the response to oxLDL with single-cell multi-omic techniques.
Supervisor: Professor Chris O’Callaghan
July. 2018 - Sept. 2020: Undergraduate Research Assistant, Dept. of Food Safety & Nutrition , Zhejiang University University, Hangzhou, ZJ, China
- Projects:
  1. PBTK modeling of acrylamide, glycidol, and 3-MCPD (thesis project)
  2. Transcriptomic and epigenetic regulation of acrylamide-induced cardiac developemental toxicity
- Supervisor: Professor Yu Zhang
July 2020 - Sept.2020: Intern, Discovery Biology, BioDuro Co. Ltd., Shanghai, SH, China
- Projects:
  1. Development of a real-time high-throughput drug screening platform using CRISPR-engineered cellline
  2. Double-transfected stable cell line generation
- Supervisor: Dr. Yanchun Guo
June 2019 - Aug. 2019: Summer Research Intern, Dept. Molecular Biology, Princeton University, Princeton, NJ, US
- Projects:
  - Forward genetic screen for genes that regulate reproductive aging in C .elegans
- Supervisor: Professor Coleen Murphy

Programming Laguanges:
- Proficient in R, Python and Unix Shell
- Experience with C and MATLAB
Well-trained in bulk & single-cell sequencing data analyses
Proficient in applying machine learning approaches to analyze complex biological data

Development of a physiologically based toxicokinetic model of 3-MCPD and glycidol in rats . Under Review
Jiahao Jiang^#, Wei Jia^#, Yu Zhang⁺
The transcriptomic landscape of immune dysregulation in Feline Infectious Peritonitis (FIP) - a fatal complication of systemic feline coronavirus infection . EMBO Workshop (2022)
T Hiron^#, S Falcone, MD Wallace, S Binks, J Jiang, K Hughes, LJ Kennedy, J Mitchell, A Psifidi, R Tarlinton, CAO’Callaghan, E Barker, LJ Davison⁺
The construction and application of physiologically based toxicokinetic models for acrylamide, glycidamide and their biomarkers in rats and humans. Chemosphere (2022)
Yaoran Li^#, Jiahao Jiang, Qiao Wang, Li Zhu, Wei Jia, Xinyu Chen, Yu Zhang⁺
PMID: 34971622 DOI: 10.1016/j.chemosphere.2021.133458

Last update: Mar 2022